Pagets disease of bone other names osteitis deformans pagets disease this 92 year old male patient presented for assessment of sudden inability to move half his bodyan incidental finding was marked thickening of the calvariumthe diploic space is widened and there are ill defined sclerotic and lucent areas throughout the cortex is thickened and irregular. Pagets disease of bone is a chronic condition that causes abnormal enlargement and weakening of bones any part of the skeleton can be affected but the most common sites include the skull spine pelvis thigh bone shin and the bone of the upper arm. Rarely bisphosphonate therapy has been linked to severe muscle joint or bone pain which might not resolve when the medication is discontinued bisphosphonates can also increase the risk of a rare condition in which a section of jawbone dies and deteriorates usually associated with active dental disease or oral surgery. Paget disease of bone is a benign disorder characterized by focal areas of increased bone turnover in one or more skeletal sites it usually affects older adults and men are at a higher risk than . Bone marrow contains high levels of fat and calories but it also has nutrients like vitamin b12 bone marrow also contains significant portions of your reference daily intake rdi of the
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